Coeliac HLA Testing (HLA DQ2/DQ8(3))

Department of Immunology

Notes

• DNA test by PCR-SSP for Coeliac Disease (not diagnostic). Should only be performed in suspected cases of Coeliac disease where serological tests are inconclusive.
• A positive HLA DQ2/DQ8 result indicates that the individual may be at increased risk of developing Coeliac disease. A negative result does not exclude the patient from having the disease, as people negative for HLA DQ2/DQ8 may also develop coeliac disease.
• Test performed by Immunology, North Bristol NHS Trust.

Sample Requirements

EDTA blood. (No patient preparation or special handling required).

Adult

2 or 4ml Lavender topped EDTA tube.

Paediatric

1ml Paediatric EDTA sample.

Time limit for add-on

3 days

Turnaround Times

21 days