Cobalt (Co) and Chromium (Cr)

Chemical Pathology

Background Information

The main indication for cobalt and chromium levels is in assessing wear of metal-on-metal hip replacements.

Patient Preparation

No specific preparation required.

Sample Requirements

Please note there is a minimum retesting interval of one year.

For adults, blood taken into a 4mL EDTA tube

Storage/Transport

Send at ambient temperature to the laboratory. If unavoidable, samples can be refrigerated overnight.

Required Information

Relevant clinical details, including the reason for the request.

Turnaround Times

The samples are sent to a referral laboratory for analysis with results expected back within three weeks.

Reference Ranges

Ranges and interpretation reported as provided by referral laboratory.

See most recent MHRA guidance for monitoring patients with metal-on-metal hip joints.

Further Information

For more information on heavy metals visit Lab Tests Online

Page last updated: 29/09/2025 | Page last reviewed: 29/09/2025