Chemical Pathology

Notes

The main indication for cobalt and chromium levels is in assessing wear of metal-on-metal hip replacements.

Sample requirements

For adults, blood taken into a 4mL EDTA tube

EDTA with cap





Storage/transport

Send at ambient temperature to the laboratory. If unavoidable, samples can be refrigerated overnight.

Required information

Relevant clinical details, including the reason for the request.

Turnaround times

The samples are sent to a referral laboraotory for analysis with results expected back within 2 weeks.

Reference ranges

Cobalt:

Less than 10 nmol/L

MHRA Cobalt threshold (7ppb) for patients with MoM hip joints 120 nmol/L

(To convert from nmol/L to µg/L - multiply by 0.059)

Chromium:

Less than 40 nmol/L

MHRA Chromium threshold (7ppb) for patients with MoM hip joints is 135 nmol/L

(To convert from nmol/L back to µg/L - multiply by 0.052)

Further information


Page last updated: 07/02/2019

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