Lupus Anticoagulant Screening

Department of Haematology

Notes

• This test can be requested as LUPUS which includes Coagulation Screen, DRVVT and Anti-cardiolipin antibodies.
• It can also be requested as part of a full Thrombophilia screen, please see the Thrombophilia Screen test page.
• In addition Beta 2 Glycoprotein 1 Antibodies IgG and IgM (B2GP1) may also be requested.
• Coagulation screen – Test performed at GRH and CGH.
• DRVVT – Test performed at GRH.
• Anti cardiolipin Abs – IgG test performed at GRH and IgM sent to PRU, Northern General Hospital, Sheffield.
• B2GP1 - Test performed at PRU, Northern General Hospital, Sheffield.

Sample Requirements

• Blood samples should ideally reach the laboratory within 2 hours. Samples greater than 24 hours old will not be tested for the coagulation screen or DRVVT.
• Coagulation tests must be performed on samples taken by clean venesection, and filled to the appropriate level (in line with black arrow or above the frosted line).
• Overfilled, underfilled and haemolysed samples will give erroneous results and will not be processed.
• Samples should not be taken from indwelling lines that have been flushed with Heparin as contamination frequently occurs despite the initial draw.
• All other sample requirements including sample bottles and the number of tubes, see individual test pages.

Turnaround Time

See individual test pages

Reference Range

See individual test pages

Time limit for add-on

See individual test pages.