Blood Transfusion


Cold haemagglutinin disease (CHAD) accounts for 16-32% of all cases of immune haemolysis. It occurs as an acute or chronic condition. The acute form is often secondary to lymphoproliferative disorders or Mycoplasma pneumoniae infection.


  • Samples for this test must be maintained at 37oC from the time collected and during transport to the laboratory.
  • An insulated box is available from the Immunology Department at GRH or Pathology Reception CGH
  • Samples which have NOT been kept at 37oC are unsuitable for testing
  • If a gold top serum gel tube is sent without an EDTA sample, the test cannot be performed.
  • The test is performed at CGH and GRH
  • This is a non-accredited test as there is no EQA scheme available

Sample Requirements

Samples for this test must be maintained at 37oC when being transported to the laboratory.

Serum tube - 6mL

Gold top with cap


6mL EDTA tube

EDTA with cap


Red TOP 6mL Serum

6ml red top tube

Required Information

Sample and request form must be labelled correctly with 4 points of reference:

  1. Unique identification number
  2. Surname
  3. First name
  4. Date of birth.

Unlabelled, wrongly labelled or inadequately labelled specimens will not be accepted. No specimen is considered unrepeatable

For further information on specimen labelling see Labelling Policy

Turnaround times

Within 24 hours