CRP (C-reactive protein)

Chemical Pathology

Notes

C-reactive protein (CRP) is a non-specific marker of infection and inflammation and is a more sensitive, rapidly responding indicator than ESR or viscosity.

Sample requirements

For adults, blood taken into a 5mL gold top tube (rust top for the Acute Unit)

For children, blood taken into a 3.5mL rust top tube

For neonates, blood taken into a 0.8mL minicollect lithium heparin tube

Storage/transport

Send at ambient temperature to the laboratory. If unavoidable, samples can be stored refrigerated overnight.

Required information

Relevant clinical details.

Turnaround times

The assays are run throughout the day and night.

The in-lab turnaround time is less than 24 hours.

The test can be ordered as an urgent request.

Reference ranges

Less than 5 mg/L for adults.

The CRP reference range may not be applicable to neonates - the immune response may be immature and CRP levels of <5 mg/L may be significant.

Further information

To learn more about CRP Lab Tests Online: C-Reactive Protein or access the monograph of the Association for Clinical Biochemistry and Laboratory Medicine (pdf)

Page last updated 11/02/2015