Cycloserine assay

Microbiology

Notes

Sample requirements

• The information given here is intended for use by healthcare professionals. Please see Lab Tests Online-UK for more general advice, links and background.
• Approx 1- 2mL of separated serum (acceptable minimum volume: 100µL). The sample is sent to a reference laboratory and transport time must be <7 days.
• Samples should be kept at 4ºC if there is a delay in sending.
• Please contact the laboratory if in doubt as sample integrity may be affected.
• Leaking samples may not be processed.

Test Information Required:

• Patient name, sex and age.
• Laboratory number.
• Dosage, frequency and timing of samples.
• Clinical summary
• Other medications (essential, esp. pyrazinamide)

Sample to be collected in a gold top serum tube.

Timing of Samples

We recommend pre does sample and a post dose sample, taken 3-4 hours after oral administration.

Result interpretation

• Results will be available within 4 days depending on the day of receipt.
• Reference range:

Ø Pre dose: 10 – 20 mg/L.

Ø Post dose: 20 – 35 mg/L

Ø Levels to be kept below 35 mg/L

Turnaround time:

<4 days

Re – assay Interval:

10 -30 days, assuming initial results are within expected range.