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Chemical Pathology Notes A requestable test profile consisting of: Total protein Albumin Alkaline phosphatase Calcium (Total and adjusted) NB: Phosphate
Investigation for suspected infantile homocystinuria Confirmation of vitamin B12 deficiency when B12 level borderline (NB: not routinely available for
Notes NB; This test is rarely required as in general adds no additional information to the usual Microbiology investigations.
NB: Protease Inhibitor Activity may also be reported as 'positive' or 'negative'.
NB if unable to distinguish between passive and immune anti-D, FMH estimation should be performed.
NB: remember enzyme activity may have been induced if patient has already begun treatment.
NB: different ApoB concentration targets may be used by specialists in treating people at high cardiovascular risk.
NB: This does not exclude the possibility of carrier status or low activity variants.
Reference ranges Serum/plasma total calcium: 2.20–2.63 mmol/L (NB: apparently raised total calcium levels up to 3.00 mmol/L in 0–3 month infants and up
In line with Gloucestershire Prescribing Guidance NB 'Freestyle Libre 2' sensors will be discontinued by Aug 2025.
NICE TA327 (NB parenteral anticoagulant treatment is required for 5 days prior to starting dabigatran for this indication)
(NB – high risk biohazardous tissues are not suitable for frozen sections.
(NB: levetiracetam granules should be prescribed as the Desitrend® brand)