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Chemical Pathology Notes A requestable test profile consisting of: Total protein Albumin Alkaline phosphatase Calcium (Total and adjusted) NB: Phosphate
Investigation for suspected infantile homocystinuria Confirmation of vitamin B12 deficiency when B12 level borderline (NB: not routinely available for
Notes NB; This test is rarely required as in general adds no additional information to the usual Microbiology investigations.
NB: Protease Inhibitor Activity may also be reported as 'positive' or 'negative'.
NB: remember enzyme activity may have been induced if patient has already begun treatment.
NB: different ApoB concentration targets may be used by specialists in treating people at high cardiovascular risk.
NB: This does not exclude the possibility of carrier status or low activity variants.
Reference ranges Serum/plasma total calcium: 2.20–2.63 mmol/L (NB: apparently raised total calcium levels up to 3.00 mmol/L in 0–3 month infants and up
NB if unable to distinguish between passive and immune anti-D, FMH estimation should be performed.
In line with Gloucestershire Prescribing Guidance NB 'Freestyle Libre 2' sensors will be discontinued by Aug 2025.
NICE TA327 (NB parenteral anticoagulant treatment is required for 5 days prior to starting dabigatran for this indication)
(NB – high risk biohazardous tissues are not suitable for frozen sections.
(NB: levetiracetam granules should be prescribed as the Desitrend® brand)