A medicine you received today as part of your anaesthetic, may interfere with hormonal contraception and increase the chance of pregnancy. If you are taking ‘the pill’ (combined or mini), follow the missed pill advice in the pill information leaflet. If you have a hormonal implant, coil, injection, patch or vaginal ring, you will need to use barrier contraception, such as condoms, for 7 days.

Why have I been given this leaflet?

Commonly, as part of your anaesthetic, drugs are administered to relax your muscles. At the end of an operation, the action of these drugs need to be reversed before you wake up. One of these ‘reversal’ drugs which you have been given today is called sugammadex.


The drug sugammadex may reduce the effectiveness of hormone contraceptives and temporarily increase the risk of pregnancy.

What should I do?

If you are taking an oral hormonal contraceptive such as the combined oral contraceptive pill (the pill) or the progesterone only contraceptive pill (the mini pill) and you have taken your pill this morning and have been given sugammadex, it is the equivalent to one missed pill.


Please follow the missed pill advice in the leaflet within the package.

If you are taking any other form of hormonal contraceptive such as:

  • Contraceptive implant (e.g. Nexplanon®)
  • Hormonal intrauterine system (e.g. Mirena® coil)
  • Hormonal injection (e.g. Depo-Provera®)
  • Contraceptive patch (e.g. EVRA®)
  • Vaginal ring (e.g. NuvaRing®)

You must use a barrier method of contraception, such as condoms, for the next 7 days and follow the advice in the leaflet within the package of the contraceptive product.

If you would like further information or you have any questions, please speak to your anaesthetist.



With grateful thanks to

  1. Dr Sahil Gupta, Clinical Fellow, Anaesthesia and Critical Care.
  2. Dr Deborah Burton, Speciality Director Anaesthetics, Critical Care, Pain and Pre-Assessment.
  3. Dr James Self, Consultant Anaesthetist.

Printable version of this page

Contraceptive advice for patients following the administration of Sugammadex GHPI1666_04_24 Department: Anaesthetics Review due: May 2027 PDF, 321.3 KB, 3 pages
Reference number GHPI1666_04_24
Department Anaesthetics
Review due May 2027