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Neonatal alloimmune thrombocytopenia (NAIT) is a condition where a mother's immune system produces antibodies against specific proteins (human platelet antigens, or HPAs) on the surface of her baby's platelets. These antibodies cross the placenta, leading to the destruction of the baby's platelets, which can result in low platelet counts (thrombocytopenia). This condition may cause symptoms ranging from mild skin bruising to severe complications like intracranial hemorrhage.
As with most tumour markers there is a high incidence of false positive and false negative results. CA 19-9 is most appropriately used in monitoring disease progression or effectiveness of treatment once diagnosis of the tumour has been made and serum concentrations have been shown to be raised prior to treatment (Lewis negative individuals do not express CA 19-9).
by Abigail Harper
This page gives you information about orthostatic hypotension, advice about how to manage the symptoms and describes some of the treatments available.
This page gives you information about what to expect when leaving the Emergency Department after having had sedation. You have been given a sedative medication to assist with your procedure. You may experience a short period of memory loss during the time the sedation is effective. This medication may also impair your judgment for up to 24 hours. Sedation is safe with very few side effects but most patients have feelings of tiredness afterwards. Some people may believe they are fine and unaffected by the medication but their reactions will be slower. This is similar to how some people may feel after having alcohol.
Deficiency of the enzyme alpha-galactosidase, results in Fabry's disease, an X-linked, recessive, lysosomal storage disease, also known as Anderson-Fabry disease.
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This page is for patients diagnosed with a cancer in the rectum (back passage). The information will help you to understand the patient pathway, and make you aware of the various treatment options that might be available to you.
This page gives you information about having a Computed Tomography (CT) guided abdominal or pelvic biopsy. It explains how the procedure is carried out and some of the possible complications.
Resolving the Phlebotomy Industrial Action
This page is to inform you about how some of your medicines will be supplied. The medicine(s) shown on this page will be delivered to you by a clinical homecare provider.
This page is to inform you about how some of your medicines will be supplied. The medicine(s) shown on this page will be delivered to you by a clinical homecare provider. The hospital clinical team uses a homecare provider to dispense and deliver certain medicines. At your hospital appointment your medication will be reviewed and a prescription written. You will not need to collect the medication from the pharmacy department in the hospital or get a prescription from your GP. Instead, your prescription will be sent directly to the homecare provider specified. Within a few days of receiving your prescription the homecare provider will call you to arrange a time and location for the delivery of your medication (and any other items required to use the medicine such as syringes). In addition to this page, you may be sent an information pack from the homecare provider. The pack will give you more details about the service they offer and provide you with the contact details of the homecare Patient Services department. This will enable you to contact them if you have any concerns or if you no longer wish to use this service.
This page gives you information about your right to refuse a transfusion of blood or blood products as part of your treatment.
How to submit a question for the Trust Board
For further information, see: Pathology policy for specimen and request form labelling for pathology users
This page gives you information on care following banding of piles (haemorrhoids).