Results for ".k"

2025

Protein S (PTS) is a Vitamin-K dependant factor which serves as a cofactor for activated Protein C in the degradation of Factors V and VIII. It circulates in blood plasma in both free and bound (to C4b binding protein) forms. Only the free portion has activity. Inherited PTS deficiency can account for recurrent thrombo-embolic episodes in young adults. Most cases are heterozygous. Acquired PTS deficiency can occur with Vitamin K deficiency, Oestroprogesterone therapy, oral anticoagulation therapy, liver disease, DIC, the third trimester of pregnancy, and in the early post-operative phase.

Protein C (PTC) is a Vitamin K dependant factor which, after activation by Thrombin, acts with it's co-factor Protein S to degrade the activated forms of Factors V and VIII. Inherited PTC deficiency accounts for 5-7% of recurrent thrombo-embolic episodes in young adults. Deficiency can be the result of a defect at the substrate binding site (qualitative, Type II deficiency) or as a result of reduced levels of otherwise normal PTC (quantitative, Type I deficiency). Most cases are heterozygous, but some homozygous cases have been described in neonates with massive visceral thrombosis and purpura fulminans. Acquired PTC deficiency can be found in Vitamin K deficiency, oral anticoagulation therapy, liver disease, DIC and in the early post-operative phase.

Department of Haematology

You have been diagnosed with endometriosis. This page gives you information about endometriosis and its treatment.

This page outlines the risks and possible complications linked to obesity and the benefits of losing weight. You may find this information useful as you have recently been given advice about how life style changes and weight loss will help to improve your fertility.

Earlier this year, our Trauma and Orthopaedics (T&O) team took steps to understand patients’ experiences of the Fracture Clinic service.

Dr Ogheneochuko Bakpa

This page will answer some of the questions you may have about Intracytoplasmic Sperm Injection (ICSI) treatment. ICSI treatment is recommended for patients who have few sperm, sperm that are not moving well, or who have in the past failed to achieve fertilisation.

Newborn babies have underdeveloped immune systems, making them particularly susceptible to infections that may be mild in adults but severe in infants

The information on this page is for women who are not ovulating on their own. Ovulation induction is a kind of fertility treatment where a daily injection of a hormone is taken to stimulate the ovary for eggs to grow.

by Dr Nesem Al-Ali

This page describes the treatment options available for men with azoospermia or severe oligospermia. ‘Azoospermia’ and severe ‘oligospermia’ are the words to describe an absence of sperm or very few sperms in the ejaculate. Various factors can contribute towards these conditions, some of which may be inherited.

Clomid® (Clomiphene citrate) or Letrozole are used in women who do not ovulate (produce eggs) regularly each month leading to infertility. These medicines stimulate eggs to develop in the ovaries and be released for fertilisation. These medications will work best for you if you maintain your BMI between 19 and 30.

This page has been given to you to answer some of the questions you may have about the karyotyping and cystic fibrosis screening which has been recommended for you.

This page will answer some of the questions you may have about the medication (metformin) you have been advised to take to help with your condition of polycystic ovaries (PCOS).

This page gives you information about the process of IVF as advised by your specialist. In Vitro Fertilisation (IVF) is an assisted method of conception which increases the chance of pregnancy by placing fertilised ova or eggs directly into the uterus or womb. The fertilised eggs are called embryos.